PocketLogin allows you to synchronize Outlook, any desktop items, and essentially any folder (directory) on your computer. So after you decide what you want to sync, and press the button, you're prepared to be wowed.
Not we've all see files move from storage medium to another, and watching it on the Migo is no different, but wait for the next step Close down Outlook, properly remove the Migo (according to your OS) and then go to another computer somewhere.
That somewhere can be the office, a friend's house, even the business center at the hotel. Plug in the Migo, double-click PocketLogin and type in your password.
You're now working on your computer. The Outlook files are there, as are the desktop items and any other folder. While I did not test sending and receiving e-mail, Outlook did attempt to look for my e-mail (I forgot to turn off Outlook on my desktop). Will you be able to access your e-mail, that probably depends on how Outlook is configured in the first place, and how your ISP (or corporate e-mail server/Exchange) are configured.
But nevertheless, you have everything you need to work, without the need of a direct connection to your desktop.